NUMB Antikörper (AA 525-575)

Produktnummer ABIN7452379

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NUMB in IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NUMB Antikörper (AA 525-575) (ABIN7452379)

Target: NUMB (Numb Homolog (NUMB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMB Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-NUMB Antikörper

Bindungsspezifität: AA 525-575

Verwendungszweck: Rabbit anti-NUMB Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 525 and 575

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-NUMB antibody ABIN7451903.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NUMB

Target: NUMB (Numb Homolog (NUMB))

Andere Bezeichnung: NUMB

Hintergrund: Background: NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.

Gen-ID: 8650

NCBI Accession: NP_001005743

UniProt: P49757

Pathways: Cell-Cell Junction Organization