CENPF Antikörper (AA 3150-3200)
Kurzübersicht für CENPF Antikörper (AA 3150-3200) (ABIN7452290)
Target
Alle CENPF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 3150-3200
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Verwendungszweck
- Rabbit anti-CENP-F/Mitosin Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 3150 and 3200
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-CENP-F/Mitosin antibody A301-617A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CENPF (Centromere Protein F (CENPF))
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Andere Bezeichnung
- CENP-F/Mitosin
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Hintergrund
- Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.
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Gen-ID
- 1063
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UniProt
- P49454
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Pathways
- Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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