BRAP Antikörper (AA 510-560)
Kurzübersicht für BRAP Antikörper (AA 510-560) (ABIN7452274)
Target
Alle BRAP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 510-560
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Verwendungszweck
- Rabbit anti-BRAP Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 510 and 560
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-BRAP antibody ABIN7451664.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- BRAP (BRCA1 Associated Protein (BRAP))
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Andere Bezeichnung
- BRAP
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Hintergrund
- Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].
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Gen-ID
- 8315
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NCBI Accession
- NP_006759
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UniProt
- Q7Z569
Target
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