FZD6 Antikörper (AA 656-706)
Kurzübersicht für FZD6 Antikörper (AA 656-706) (ABIN7452245)
Target
Alle FZD6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 656-706
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Verwendungszweck
- Rabbit anti-Frizzled-6 Antibody, Affinity Purified
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Homologie
- Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 656 and 706
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7452245 has not performed satisfactorily when used for WB of Frizzled-6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Frizzled-6.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Andere Bezeichnung
- Frizzled-6
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Hintergrund
- Background: Frizzled-6 is a receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin, and activation of wnt target genes. In mice, frizzled-6 is critical to B-cell development.
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Gen-ID
- 8323
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NCBI Accession
- NP_003497
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UniProt
- O60353
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Pathways
- WNT Signalweg, Tube Formation
Target
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