CDKN1C Antikörper (AA 266-316)
Kurzübersicht für CDKN1C Antikörper (AA 266-316) (ABIN7452239)
Target
Alle CDKN1C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 266-316
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Verwendungszweck
- Rabbit anti-p57kip2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 266 and 316
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7452239 has not performed satisfactorily when used for WB of p57KIP2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of p57KIP2.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Andere Bezeichnung
- p57kip2
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Hintergrund
- Background: p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate [taken from NCBI GeneID:1028].
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Gen-ID
- 1028
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NCBI Accession
- NP_000067
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UniProt
- P49918
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Pathways
- Zellzyklus, Dopaminergic Neurogenesis
Target
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