STUB1 Antikörper (AA 1-50)
Kurzübersicht für STUB1 Antikörper (AA 1-50) (ABIN7452073)
Target
Alle STUB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-STUB1/CHIP Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1 and 50
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Isotyp
- IgG
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anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Schwein, Pferd, Affe, Huhn, Hamster, Avian, Cat, Esel, Ziege, Kaninchen, Schaf WB Wirt: Ziege Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodyVerified STUB1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibodySTUB1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231), (C-Term) antibodySTUB1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7393 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibodySTUB1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-48) antibodySTUB1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 236-263), (C-Term) antibodySTUB1 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB32217 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (N-Term) antibodySTUB1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
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Andere Bezeichnung
- STUB1/CHIP
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Hintergrund
- Background: STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimers and Down's syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53.
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Gen-ID
- 10273
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NCBI Accession
- NP_005852
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UniProt
- Q9UNE7
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Pathways
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
Target
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