PPP2R3B Antikörper (AA 350-400)
Kurzübersicht für PPP2R3B Antikörper (AA 350-400) (ABIN7451975)
Target
Alle PPP2R3B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 350-400
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Verwendungszweck
- Rabbit anti-PPP2R3B Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 350 and 400
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))
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Andere Bezeichnung
- PPP2R3B
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Hintergrund
- Background: PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. It is a trimeric holoenzyme that is comprised of a catalytic, structural, and regulatory subunit. PPP2R3B is a regulatory subunit of PP2A. The regulatory subunits of PP2A are grouped into 3 families: B/PR55, B'/PR61, and B''/PR72. PPP2R3B encodes a 48 kDa B'' regulatory subunit. PPP2R3B and PP2A, in association with Cdc6, are implicated in cell cycle control via phosphatase activity targeted at DNA replication machinery. serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B, PP2A subunit B PR48 isoform, PPP2R3L, PR48, NY-REN-8, PPP2R3LY.
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Gen-ID
- 28227
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NCBI Accession
- NP_037371
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UniProt
- Q9Y5P8
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Pathways
- PI3K-Akt Signalweg, Mitotic G1-G1/S Phases
Target
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