KDM4C Antikörper (AA 475-525)
Kurzübersicht für KDM4C Antikörper (AA 475-525) (ABIN7451826)
Target
Alle KDM4C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 475-525
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Verwendungszweck
- Rabbit anti-JMJD2C Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 475 and 525
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
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Andere Bezeichnung
- JMJD2C
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Hintergrund
- Background: JMJD2C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2C, also known as GASC1 (gene amplified in squamous cell carcinoma), has been found to be amplified in several esophageal squamous carcinomas and inhibition of JMJD2C/GASC1 expression results in decreased cellular proliferation.
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Gen-ID
- 23081
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NCBI Accession
- NP_055876
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UniProt
- Q9H3R0
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Pathways
- Nuclear Hormone Receptor Binding, Warburg Effekt
Target
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