Huntingtin Antikörper (AA 1150-1200)
Kurzübersicht für Huntingtin Antikörper (AA 1150-1200) (ABIN7451812)
Target
Alle Huntingtin (HTT) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1150-1200
-
Verwendungszweck
- Rabbit anti-Huntingtin Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 1150 and 1200
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- Huntingtin (HTT)
-
Andere Bezeichnung
- Huntingtin
-
Hintergrund
- Background: The Huntingtin (HTT) gene is linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range in the number of trinucleotide repeats has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene product is widely expressed and is required for normal development [taken from NCBI Entrez Gene (Gene ID: 3064)].
-
Gen-ID
- 3064
-
NCBI Accession
- NP_002102
-
UniProt
- P42858
-
Pathways
- PI3K-Akt Signalweg, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
Target
-