GEMIN5 Antikörper (AA 1410-1438)

Produktnummer ABIN7451795

Der Kaninchen Polyklonal Anti-GEMIN5-Antikörper wurde für WB und IP validiert. Er ist geeignet, GEMIN5 in Proben von Human zu detektieren.

Kurzübersicht für GEMIN5 Antikörper (AA 1410-1438) (ABIN7451795)

Target: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GEMIN5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-GEMIN5 Antikörper

Bindungsspezifität: AA 1410-1438

Verwendungszweck: Rabbit anti-Gemin5 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1410 and 1438

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu GEMIN5

Target: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Andere Bezeichnung: Gemin5

Hintergrund: Background: Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.

Gen-ID: 25929

NCBI Accession: NP_056280

UniProt: Q8TEQ6

Pathways: Ribonucleoprotein Complex Subunit Organization