DFFA Antikörper (C-Term)
Kurzübersicht für DFFA Antikörper (C-Term) (ABIN7451735)
Target
Alle DFFA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-DFF35/DFFA Antibody, Affinity Purified
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Homologie
- Monkey
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Aufreinigung
- Affinity Purified
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Immunogen
- C-terminus
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
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Andere Bezeichnung
- DFF35/DFFA
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Hintergrund
- Background: DFF (DNA fragmentation factor) is the principle endonuclease responsible for DNA cleavage during apoptosis and exists as a heterodimer formed between the inhibitory subunit, DFF45, and the DNA nuclease, DFF40. DFF35/DFFA is a 35 kDa splice variant of the inhibitory subunit, DFF45. Similar to DFF45, DFF35 has been shown to heterodimerize with DFF40 and also negatively regulate its nuclease activity. In addition to regulating DFF40 activity, DFF35 has also been found to assist in the synthesis and folding of the DFF40 endonuclease.
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Gen-ID
- 1676
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NCBI Accession
- NP_998731
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UniProt
- O00273
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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