IGKV1-27 Antikörper (AA 525-575)
Kurzübersicht für IGKV1-27 Antikörper (AA 525-575) (ABIN7451604)
Target
Alle IGKV1-27 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 525-575
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Verwendungszweck
- Rabbit anti-A20 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 525 and 575
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))
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Andere Bezeichnung
- A20
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Hintergrund
- Background: Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) P21580].
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Gen-ID
- 7128
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NCBI Accession
- NP_006281
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UniProt
- P21580
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Pathways
- Activation of Innate immune Response
Target
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