UBXN1 Antikörper (AA 262-312)
Kurzübersicht für UBXN1 Antikörper (AA 262-312) (ABIN7451534)
Target
Alle UBXN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 262-312
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Verwendungszweck
 - Rabbit anti-UBXN1 Antibody, Affinity Purified
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Homologie
 - Mouse,Rat,Bovine
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Aufreinigung
 - Affinity Purified
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Immunogen
 - between AA 262 and 312
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Isotyp
 - IgG
 
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 1000 μg/mL
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Buffer
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C
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Haltbarkeit
 - 12 months
 
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- UBXN1 (UBX Domain Protein 1 (UBXN1))
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Andere Bezeichnung
 - UBXN1
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Hintergrund
 - Background: UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1.
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Gen-ID
 - 51035
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NCBI Accession
 - NP_056937
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UniProt
 - Q04323
 
Target
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