UBXN1 Antikörper

Produktnummer ABIN7246250

Produktdetails anti-UBXN1 Antikörper

Target: UBXN1 (UBX Domain Protein 1 (UBXN1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBXN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UBXN1

Target: UBXN1 (UBX Domain Protein 1 (UBXN1))

Andere Bezeichnung: UBXN1 (UBXN1 Produkte)

Synonyme: 2B28 antikoerper, SAKS1 antikoerper, UBXD10 antikoerper, 4930455J02Rik antikoerper, D19Ertd721e antikoerper, T25529 antikoerper, RGD1309471 antikoerper, fb49a05 antikoerper, wu:fb49a05 antikoerper, zgc:77531 antikoerper, UBX domain protein 1 antikoerper, UBXN1 antikoerper, Ubxn1 antikoerper, ubxn1 antikoerper

Hintergrund: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 33 kDa

UniProt: Q04323