LIN54 Antikörper (AA 50-100)
Kurzübersicht für LIN54 Antikörper (AA 50-100) (ABIN7451470)
Target
Alle LIN54 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 50-100
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Verwendungszweck
- Rabbit anti-LIN54 Antibody, Affinity Purified
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Homologie
- Mouse,Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 50 and 100
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- LIN54 (Lin-54 Homolog (LIN54))
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Andere Bezeichnung
- LIN54
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Hintergrund
- Background: LIN54 is a component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, LIN54 acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner [taken from the Universal Protein Resource (UniProt) Q6MZP7].
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Gen-ID
- 132660
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NCBI Accession
- NP_919258
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UniProt
- Q6MZP7
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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