VRK1 Antikörper (AA 1-50)

Produktnummer ABIN7451384

Der Kaninchen Polyklonal Anti-VRK1-Antikörper wurde für IP validiert. Er ist geeignet, VRK1 in Proben von Human zu detektieren.

Kurzübersicht für VRK1 Antikörper (AA 1-50) (ABIN7451384)

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VRK1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-VRK1 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-VRK1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-VRK1 antibody ABIN7450901.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu VRK1

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Andere Bezeichnung: VRK1

Hintergrund: Background: Vaccinia-related kinase 1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.VRK1 is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This protein, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN [taken from NCBI Entrez Gene (Gene ID: 7443)].

Gen-ID: 7443

UniProt: Q99986