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VRK1 Antikörper

VRK1 Reaktivität: Human WB Wirt: Maus Monoclonal 5C1 unconjugated
Produktnummer ABIN4915154
  • Target Alle VRK1 Antikörper anzeigen
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    Reaktivität
    • 41
    • 11
    • 4
    Human
    Wirt
    • 35
    • 6
    Maus
    Klonalität
    • 37
    • 4
    Monoklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VRK1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 15
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogen
    Purified His-tagged VRK1 protein was used to produced this monoclonal antibody.
    Klon
    5C1
    Isotyp
    IgG1
    Top Product
    Discover our top product VRK1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    Andere Bezeichnung
    VRK1 (VRK1 Produkte)
    Synonyme
    vrk1 antikoerper, MGC64390 antikoerper, MGC75762 antikoerper, VRK1 antikoerper, PCH1 antikoerper, PCH1A antikoerper, 51PK antikoerper, wu:fe16f06 antikoerper, zgc:56266 antikoerper, vaccinia related kinase 1 L homeolog antikoerper, vaccinia related kinase 1 antikoerper, Serine/threonine-protein kinase VRK1 antikoerper, vrk1.L antikoerper, vrk1 antikoerper, VRK1 antikoerper, vrk-1 antikoerper, Vrk1 antikoerper
    Hintergrund

    Synonyms: PCH1, PCH1A, Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1, VRK1

    Background: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

    Gen-ID
    7443
    UniProt
    Q99986
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