ERBB3 Antikörper (AA 1275-1325)
Kurzübersicht für ERBB3 Antikörper (AA 1275-1325) (ABIN7451238)
Target
Alle ERBB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1275-1325
-
Verwendungszweck
- Rabbit anti-ErbB3 Antibody, Affinity Purified
-
Homologie
- Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- Between AA 1275 and 1325
-
Isotyp
- IgG
-
-
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 707-964) antibody
ERBB3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55), (N-Term) antibodyERBB3 Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB01467 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibodyERBB3 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) antibodyERBB3 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2E9 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibodyERBB3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) antibodyERBB3 Reaktivität: Human WB, IP, IHC (fro), IHC (f) Wirt: Maus Monoclonal RTJ-1 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55) antibodyERBB3 Reaktivität: Human, Maus WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1328) antibodyERBB3 Reaktivität: Human, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 661-760) antibodyERBB3 Reaktivität: Human, Maus, Ratte ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibodyERBB3 Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB25837 unconjugated
-
-
Applikationshinweise
-
IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-ErbB3 antibody ABIN7449726.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
-
Andere Bezeichnung
- ErbB3
-
Hintergrund
- Background: ErbB3, also known as HER3, is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors[taken from NCBI Entrez Gene (Gene ID: 2065)].
-
Gen-ID
- 2065
-
NCBI Accession
- NP_001973
-
UniProt
- P21860
-
Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
-
