MTMR6 Antikörper (AA 571-621)

Produktnummer ABIN7451181

Produktdetails anti-MTMR6 Antikörper

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Bindungsspezifität: AA 571-621

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTMR6 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-MTMR6 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 571 and 621

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451181 has not performed satisfactorily when used for WB of MTMR6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MTMR6.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MTMR6

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Andere Bezeichnung: MTMR6 (MTMR6 Produkte)

Synonyme: 4022440C11Rik antikoerper, AI428804 antikoerper, AU041072 antikoerper, zgc:55289 antikoerper, wu:fi04a11 antikoerper, si:dkey-286f3.1 antikoerper, zgc:56405 antikoerper, myotubularin related protein 6 antikoerper, myotubularin related protein 8 antikoerper, MTMR6 antikoerper, Mtmr6 antikoerper, mtmr6 antikoerper, mtmr8 antikoerper

Hintergrund: Background: Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) Q9Y217].

Gen-ID: 9107

UniProt: Q9Y217

Pathways: Inositol Metabolic Process