MTMR6 Antikörper (AA 571-621)
Kurzübersicht für MTMR6 Antikörper (AA 571-621) (ABIN7451181)
Target
Alle MTMR6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 571-621
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Verwendungszweck
- Rabbit anti-MTMR6 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 571 and 621
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451181 has not performed satisfactorily when used for WB of MTMR6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MTMR6.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MTMR6 (Myotubularin Related Protein 6 (MTMR6))
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Andere Bezeichnung
- MTMR6
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Hintergrund
- Background: Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) Q9Y217].
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Gen-ID
- 9107
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UniProt
- Q9Y217
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Pathways
- Inositol Metabolic Process
Target
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