Neurofibromin 1 Antikörper (AA 150-200)
Kurzübersicht für Neurofibromin 1 Antikörper (AA 150-200) (ABIN7451098)
Target
Alle Neurofibromin 1 (NF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 150-200
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                                            Verwendungszweck
- Rabbit anti-NF1 Antibody, Affinity Purified
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                                            Homologie
- Mouse,Rat
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                                            Aufreinigung
- Affinity Purified
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                                            Immunogen
- Between AA 150 and 200
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- 
                        IP: 2 - 10 μg/mg lysate WB: Not recommended. ABIN7451098 has not performed satisfactorily when used for WB of NF1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of NF1. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Konzentration
- 1000 μg/mL
- 
                                            Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - Neurofibromin 1 (NF1)
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                                            Andere Bezeichnung
- NF1
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                                            Hintergrund
- Background: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.
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                                            Gen-ID
- 4763
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                                            NCBI Accession
- NP_001035957
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                                            UniProt
- P21359
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                                            Pathways
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
 Target
- 
                    
 
                                     
                                     
                                    