Neurofibromin 1 Antikörper (AA 1551-1600)
Kurzübersicht für Neurofibromin 1 Antikörper (AA 1551-1600) (ABIN1534476)
Target
Alle Neurofibromin 1 (NF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1551-1600
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Verwendungszweck
- Neurofibromin Antibody
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Spezifität
- Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Neurofibromin 1 (NF1)
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Andere Bezeichnung
- NF1
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Hintergrund
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Synonyms: NF1; Neurofibromin; Neurofibromatosis-related protein NF-1
Background: This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: NF1
Protein Name: Neurofibromin
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Molekulargewicht
- 319 kDa
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Gen-ID
- 4763
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OMIM
- 114500
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UniProt
- P21359
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Pathways
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
Target
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