UPF3B Antikörper (AA 300-350)
Kurzübersicht für UPF3B Antikörper (AA 300-350) (ABIN7450880)
Target
Alle UPF3B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 300-350
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Verwendungszweck
- Rabbit anti-UPF3B Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 300 and 350
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Isotyp
- IgG
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anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 416-452), (C-Term) antibody
UPF3B Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 319-423) antibodyUPF3B Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (N-Term) antibodyUPF3B Reaktivität: Human, Rind (Kuh) WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) antibodyUPF3B Reaktivität: Human, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (N-Term) antibodyUPF3B Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Schwein, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 1-180) antibodyUPF3B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 252-301) antibodyUPF3B Reaktivität: Human, Hund, Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
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Andere Bezeichnung
- UPF3B
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Hintergrund
- Background: UPF3B (UPF regulator of nonsense transcripts homolog B) is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. UPF3B recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2, UPF3B stimulates both ATPase and RNA helicase activities of UPF1 [taken from the Universal Protein Resource (UniProt) Q9BZI7].
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Gen-ID
- 65109
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NCBI Accession
- NP_542199
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UniProt
- Q9BZI7
Target
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