SYK Antikörper (AA 350-400)
Kurzübersicht für SYK Antikörper (AA 350-400) (ABIN7450791)
Target
Alle SYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 350-400
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Verwendungszweck
- Rabbit anti-SYK Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Pig
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 350 and 400
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SYK (Spleen tyrosine Kinase (SYK))
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Andere Bezeichnung
- SYK
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Hintergrund
- Background: SYK (spleen tyrosine kinase) is a ubiquitously expressed tyrosine kinase that functions in mediating B and T-cell receptor signaling and is also important to various aspects of leukocyte function that involve cytoskeleton remodeling. In mediating hematopoietic cell signaling, SYK is a substrate of src family kinase activity and is a key-regulator of Akt kinase activity. SYK has also been found to be highly expressed in the mammary gland and has been shown to inhibit tumor growth and metastasis. Invasive breast tumor cell lines have been shown to exhibit reduced or absent levels of SYK, further implicating a role in tumorigenesis and metastasis.
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Gen-ID
- 6850
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NCBI Accession
- NP_003168
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UniProt
- P43405
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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