Strumpellin Antikörper (AA 1109-1159)
Kurzübersicht für Strumpellin Antikörper (AA 1109-1159) (ABIN7450762)
Target
Alle Strumpellin (WASHC5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1109-1159
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Verwendungszweck
- Rabbit anti-SPG8/Strumpellin Antibody, Affinity Purified
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Homologie
- Zebrafish,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1109 and 1159
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))
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Andere Bezeichnung
- SPG8/Strumpellin
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Hintergrund
- Background: SPG8/Strumpellin acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). SPG8/Strumpellin may be involved in axonal outgrowth [taken from the Universal Protein Resource (UniProt) Q12768].
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Gen-ID
- 9897
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UniProt
- Q12768
Target
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