Strumpellin Antikörper (C-Term)

Produktnummer ABIN1450091

Produktdetails anti-Strumpellin Antikörper

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Strumpellin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: A 19 amino acid synthetic peptide near the carboxy terminus of Human Strumpellin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Strumpellin

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Andere Bezeichnung: Strumpellin (WASHC5 Produkte)

Synonyme: SPG8 antikoerper, AL022848 antikoerper, C76463 antikoerper, Kiaa0196 antikoerper, mKIAA0196 antikoerper, strumpellin antikoerper, WASH complex subunit 5 antikoerper, WASHC5 antikoerper, washc5 antikoerper, Washc5 antikoerper

Hintergrund: Strumpellin is a ubiquitously expressed, multi-transmembrane and spectrin-repeat-containing protein. It is named for Strumpell disease, a progressive upper-motor neurodegenerative disease termed hereditary spastic paraplegia (HSP). The Strumpellin gene maps to the eighth HSP locus (SPG8) on chromosome 8p24.13. Three families liked to this locus have mutations in the Strumpellin gene, rescue studies of zebrafish with decreased Strumpellin expression with Strumpellin mRNA containing these mutations showed impaired normal function of this protein. Recent studies suggest that Strumpellin may also be involved in protein aggregation diseases.Synonyms: KIAA0196

Gen-ID: 9897

NCBI Accession: NP_055661