Prohibitin 2 Antikörper (AA 225-275)
Kurzübersicht für Prohibitin 2 Antikörper (AA 225-275) (ABIN7450649)
Target
Alle Prohibitin 2 (PHB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 225-275
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Verwendungszweck
- Rabbit anti-REA Antibody, Affinity Purified
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Homologie
- Rat,Bovine,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 225 and 275
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Prohibitin 2 (PHB2)
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Andere Bezeichnung
- REA
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Hintergrund
- Background: REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.
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Gen-ID
- 11331
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NCBI Accession
- NP_009204
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UniProt
- Q99623
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
-