PHLPP2 Antikörper (C-Term)
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- Target Alle PHLPP2 Antikörper anzeigen
- PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PHLPP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-PHLPPL Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 1275 and C-term
- Isotyp
- IgG
- Top Product
- Discover our top product PHLPP2 Primärantikörper
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anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 1295-1323), (C-Term) antibody
PHLPP2 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB15007 unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibodyPHLPP2 Reaktivität: Human, Maus WB, ELISA, IHC, IHC (p), IP Wirt: Kaninchen Polyclonal unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 4-31), (N-Term) antibodyPHLPP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB15006 unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibodyVerified PHLPP2 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
- Andere Bezeichnung
- PHLPPL (PHLPP2 Produkte)
- Synonyme
- PHLPPL antikoerper, phlppl antikoerper, AI481772 antikoerper, C130044A18Rik antikoerper, Phlppl antikoerper, RGD1562857 antikoerper, PH domain and leucine rich repeat protein phosphatase 2 antikoerper, PH domain and leucine rich repeat protein phosphatase 2 S homeolog antikoerper, PHLPP2 antikoerper, phlpp2.S antikoerper, phlpp2 antikoerper, Phlpp2 antikoerper
- Hintergrund
- Background: PHLPPL (PH domain leucine-rich repeat-containing protein phosphatase-like) is responsible for the dephosphorylation and subsequent inactivation of Akt. Akt is a signaling protein critical to the balance of cell survival and apoptosis. Dephosphorylation of Akt by PHLPPL has been demonstrated to trigger apoptosis and suppress tumor cell growth. PHLPPL is also known as PHLPPL2 and functions similarly to its relative, PHLPP1. Recent studies show that PHLPPL and PHLPP selectively terminate Akt-signaling by targeting specific Akt isoforms.
- Gen-ID
- 23035
- NCBI Accession
- NP_055835
- UniProt
- Q6ZVD8
- Pathways
- PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung
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