PAK4 Antikörper (AA 25-75)

Produktnummer ABIN7450536

Dieses Anti-PAK4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PAK4 in WB und IP. Geeignet für Human und Maus.

Kurzübersicht für PAK4 Antikörper (AA 25-75) (ABIN7450536)

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-PAK4 Antikörper

Bindungsspezifität: AA 25-75

Verwendungszweck: Rabbit anti-PAK4 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 25 and 75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Andere Bezeichnung: PAK4

Hintergrund: Background: PAK4 is a member of the PAK family of serine/threonine p21-activating kinases. PAK4 is a target for the GTP-bound Rho GTPase, CDC42, and is an important factor that links Rho GTPases such as Ras to transformation. In this context, PAK4 is highly transforming, and has been found to be highly expressed in some tumor cell lines. PAK4 has been demonstrated to activate the JNK pathway and mediate the formation of filopodia and the reorganization of the actin cytoskeleton. PAK4 has also been found to function as a regulator of prosurvival pathways and senescence.

Gen-ID: 10298

NCBI Accession: NP_005875

UniProt: O96013

Pathways: RTK Signalweg