NBR1 Antikörper (AA 916-966)

Produktnummer ABIN7450479

Produktdetails anti-NBR1 Antikörper

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Bindungsspezifität: AA 916-966

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-NBR1 Antibody, Affinity Purified

Homologie: Orangutan

Aufreinigung: Affinity Purified

Immunogen: Between AA 916 and 966

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NBR1

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Andere Bezeichnung: NBR1 (NBR1 Produkte)

Synonyme: fa99f08 antikoerper, wu:fa99f08 antikoerper, MGC69008 antikoerper, NBR1 antikoerper, 1A1-3B antikoerper, M17S2 antikoerper, mKIAA0049 antikoerper, Ca125 antikoerper, RGD1311421 antikoerper, neighbor of brca1 gene 1a antikoerper, neighbor of BRCA1 gene 1 L homeolog antikoerper, NBR1, autophagy cargo receptor antikoerper, neighbor of Brca1 gene 1 antikoerper, nbr1a antikoerper, nbr1.L antikoerper, NBR1 antikoerper, Nbr1 antikoerper

Hintergrund: Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].

Gen-ID: 4077

UniProt: Q14596

Pathways: Autophagie