NBR1 Antikörper (AA 916-966)
Kurzübersicht für NBR1 Antikörper (AA 916-966) (ABIN7450479)
Target
Alle NBR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 916-966
-
Verwendungszweck
- Rabbit anti-NBR1 Antibody, Affinity Purified
-
Homologie
- Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- Between AA 916 and 966
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
-
Andere Bezeichnung
- NBR1
-
Hintergrund
- Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].
-
Gen-ID
- 4077
-
UniProt
- Q14596
-
Pathways
- Autophagie
Target
-