Adenylosuccinate Lyase Antikörper (AA 200-250)
Kurzübersicht für Adenylosuccinate Lyase Antikörper (AA 200-250) (ABIN7449945)
Target
Alle Adenylosuccinate Lyase (ADSL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 200-250
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Verwendungszweck
- Rabbit anti-Adenylosuccinate Lyase/ADSL Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 200 and 250
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Adenylosuccinate Lyase (ADSL)
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Andere Bezeichnung
- Adenylosuccinate Lyase/ADSL
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Hintergrund
- Background: Adenylosuccinate Lyase / ADSL is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and, in some cases, growth retardation associated with muscle wasting and epilepsy [taken from NCBI Entrez Gene (Gene ID: 158)].
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Gen-ID
- 158
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UniProt
- P30566
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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