SREBF chaperone Antikörper (AA 450-500)
Kurzübersicht für SREBF chaperone Antikörper (AA 450-500) (ABIN7449916)
Target
Alle SREBF chaperone (SCAP) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 450-500
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Verwendungszweck
- Rabbit anti-SCAP Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 450 and 500
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SREBF chaperone (SCAP)
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Andere Bezeichnung
- SCAP
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Hintergrund
- Background: Sterol regulatory element-binding protein cleavage-activating protein (SCAP) is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, SCAP binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis [taken from NCBI Entrez Gene (Gene ID: 22937)].
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Gen-ID
- 22937
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NCBI Accession
- NP_036367
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UniProt
- Q12770
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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