MAML1 Antikörper (AA 75-125)
Kurzübersicht für MAML1 Antikörper (AA 75-125) (ABIN7449893)
Target
Alle MAML1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 75-125
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Verwendungszweck
- Rabbit anti-MAML1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 75 and 125
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MAML1 (Mastermind-Like 1 (MAML1))
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Andere Bezeichnung
- MAML1
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Hintergrund
- Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
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Gen-ID
- 9794
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NCBI Accession
- NP_055572
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UniProt
- Q92585
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Pathways
- Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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