Selenoprotein S Antikörper (AA 125-175)

Produktnummer ABIN7449819

Dieses Anti-Selenoprotein S-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Selenoprotein S in WB und IP. Geeignet für Human.

Kurzübersicht für Selenoprotein S Antikörper (AA 125-175) (ABIN7449819)

Target: Selenoprotein S (SELS)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selenoprotein S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Selenoprotein S Antikörper

Bindungsspezifität: AA 125-175

Verwendungszweck: Rabbit anti-Selenoprotein S Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 125 and 175

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Selenoprotein S

Target: Selenoprotein S (SELS)

Andere Bezeichnung: Selenoprotein S

Hintergrund: Background: Selenoprotein S (SELS) is involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Selenoprotein S participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. It probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination [taken from the Universal Protein Resource (UniProt) Q9BQE4].

Gen-ID: 55829

NCBI Accession: NP_982298

UniProt: Q9BQE4

Pathways: Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom