Neurofibromin 1 Antikörper (C-Term)
Kurzübersicht für Neurofibromin 1 Antikörper (C-Term) (ABIN7449677)
Target
Alle Neurofibromin 1 (NF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- C-Term
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                                            Verwendungszweck
- Rabbit anti-NF1 Antibody, Affinity Purified
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                                            Homologie
- Rat
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                                            Aufreinigung
- Affinity Purified
- 
                                            Immunogen
- between AA 2760 and C-term
- 
                                            Isotyp
- IgG
 
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- 
    
- 
    - 
                                            Applikationshinweise
- 
                        IP: 2 - 10 μg/mg lysate WB: 1:1,000 - 1:10,000 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Konzentration
- 1000 μg/mL
- 
                                            Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - Neurofibromin 1 (NF1)
- 
                                            Andere Bezeichnung
- NF1
- 
                                            Hintergrund
- Background: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.
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                                            Gen-ID
- 4763
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                                            NCBI Accession
- NP_000258
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                                            UniProt
- P21359
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                                            Pathways
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
 Target
- 
                    
 
                                     
                                     
                                    