ube3a Antikörper (AA 400-450)
Kurzübersicht für ube3a Antikörper (AA 400-450) (ABIN7449675)
Target
Alle ube3a Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-450
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Verwendungszweck
- Rabbit anti-E6AP Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 400 and 450
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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Andere Bezeichnung
- E6AP
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Hintergrund
- Background: E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.
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Gen-ID
- 7337
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NCBI Accession
- NP_000453
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UniProt
- Q05086
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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