Prohibitin 2 Antikörper (C-Term)
Kurzübersicht für Prohibitin 2 Antikörper (C-Term) (ABIN7449571)
Target
Alle Prohibitin 2 (PHB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Verwendungszweck
- Rabbit anti-REA Antibody, Affinity Purified
-
Homologie
- Rat,Bovine,Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 250 and C-term
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 1 - 4 μg/mg lysate
WB: 1:1,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- Prohibitin 2 (PHB2)
-
Andere Bezeichnung
- REA
-
Hintergrund
- Background: REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.
-
Gen-ID
- 11331
-
NCBI Accession
- NP_009204
-
UniProt
- Q99623
-
Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
-