Rekombinanter CD80 Antikörper (AA 35-246)
Kurzübersicht für Rekombinanter CD80 Antikörper (AA 35-246) (ABIN7449415)
Target
Alle CD80 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 35-246
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Verwendungszweck
- Rabbit anti-CD80 Recombinant Monoclonal Antibody [BLR206K]
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Immunogen
- residues 35-246 (ECD)
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections. Extended primary antibody incubation (16 hours - 24 hours) is recommended.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CD80
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Andere Bezeichnung
- CD80
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Hintergrund
- Background: CD80 is a membrane receptor involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [taken from the Universal Protein Resource (UniProt) P33681].
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Gen-ID
- 941
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NCBI Accession
- NP_005182
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UniProt
- P33681
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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