MCM2 Antikörper (pSer53)
Kurzübersicht für MCM2 Antikörper (pSer53) (ABIN7449369)
Target
Alle MCM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer53
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Verwendungszweck
- Rabbit anti-Phospho MCM2 (S53) Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- surrounding serine 53
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:1,000 - 1:2,500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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Andere Bezeichnung
- MCM2
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Hintergrund
- Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.
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Gen-ID
- 4171
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NCBI Accession
- NP_004517
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UniProt
- P49736
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Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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