APOE Antikörper (HRP)

Produktnummer ABIN7449332

Der Ziege Polyklonal Anti-APOE-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, APOE in Proben von Human zu detektieren.

Kurzübersicht für APOE Antikörper (HRP) (ABIN7449332)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA

Klon: H10

Produktdetails anti-APOE Antikörper (HRP)

Verwendungszweck: Goat anti-Human Apo E [H10] Antibody HRP Conjugated

Immunogen: Human Apolipoprotein E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:1,000 - 1:8,000

ELISA: 1:1,000 - 1:8,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 50 mM PBS, 0.1 M NaCl, and 0.01 % Thiomersal, pH 7.4

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: ApoE

Hintergrund: Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

Gen-ID: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism