APOE Antikörper (Biotin)

Produktnummer ABIN7449331

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch APOE in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für APOE Antikörper (Biotin) (ABIN7449331)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Klon: B10

Produktdetails anti-APOE Antikörper (Biotin)

Verwendungszweck: Goat anti-Human Apo E [B10] Antibody Biotin Conjugated

Immunogen: Human Apolipoprotein E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:1,000 - 1:8,000

ELISA: 1:1,000 - 1:8,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: ApoE

Hintergrund: Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

Gen-ID: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism