MERTK Antikörper (AA 200-250)
Kurzübersicht für MERTK Antikörper (AA 200-250) (ABIN7449268)
Target
Alle MERTK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 200-250
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Verwendungszweck
- Rabbit anti-MerTK/c-mer Antibody, Affinity Purified
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Homologie
- Panda,Orangutan,Monkey,Chimpanzee
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 200 and 250
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Isotyp
- IgG
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Applikationshinweise
- 1:5,000 - 1:20,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
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Andere Bezeichnung
- MerTK/c-mer
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Hintergrund
- Background: MerTK/c-mer is one of three members (Tyro3, Axl, and MerTK/c-mer) of the Tyro 3 subfamily of receptor tyrosine kinases (RTK). MerTK/c-mer was cloned from a human B-lymphoblastoid cDNA library. MerTK/c-mer Expression is absent in normal lymphocytes but is found to be ectopically expressed in lymphoblasts and in T-cell ALL cell lines. When activated MerTK/c-mer transmits antiapoptotic and transforming signals and may play a significant role in T-cell leukemogenesis.
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Gen-ID
- 10461
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NCBI Accession
- NP_006334
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UniProt
- Q12866
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Pathways
- RTK Signalweg
Target
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