p107 Antikörper (AA 1018-1068)
Kurzübersicht für p107 Antikörper (AA 1018-1068) (ABIN7449079)
Target
Alle p107 (RBL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1018-1068
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Verwendungszweck
- Rabbit anti-RBL1 Antibody, Affinity Purified
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Homologie
- Mouse
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1018 and 1068
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Isotyp
- IgG
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibody
RBL1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibodyRBL1 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (C-Term) antibodyRBL1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 201-500) antibodyRBL1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 Reaktivität: Human, Maus, Rind (Kuh), Pferd, Schwein, Hund, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (N-Term) antibodyRBL1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- 6 - 15 μL/mg lysate
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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Andere Bezeichnung
- RBL1
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Hintergrund
- Background: Retinoblastoma-like protein 1 (RBL1) is a key regulator of entry into cell division. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. RBL1 recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. It controls histone H4 'Lys-20' trimethylation. RBL1 probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. It is a potent inhibitor of E2F-mediated trans-activation. RBL1 forms a complex with adenovirus E1A and with SV40 large T antigen and may bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. RBL1 may act as a tumor suppressor [taken from the Universal Protein Resource (UniProt) P28749].
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Gen-ID
- 5933
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UniProt
- P28749
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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