RAD9A Antikörper (C-Term)
Kurzübersicht für RAD9A Antikörper (C-Term) (ABIN7449007)
Target
Alle RAD9A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-Rad9 IHC Antibody, Affinity Purified
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Homologie
- Bovine,Dog,Pig,Panda,Monkey,Gorilla,Crab-eating macaque,Small-eared galago,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset,Ferret
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 350 and C-term
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Isotyp
- IgG
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Applikationshinweise
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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Andere Bezeichnung
- Rad9
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Hintergrund
- Background: Rad9 is a cell-cycle checkpoint protein with 3'-5' exonuclease activity and is part of the 9-1-1 complex. The 9-1-1 complex, also called the checkpoint clamp, is a trimeric complex that includes Rad9, Hus1, and Rad1. This complex is recruited by the RAD17/RFC clamp loader to DNA lesions where it aids in the activation of Chk2 by ATM and ATRIP and the subsequent triggering of the checkpoint signaling cascade. In addition to its role in sensing DNA damage, Rad9 also functions in the base excision repair process of DNA repair.
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Gen-ID
- 5883
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NCBI Accession
- NP_004575
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UniProt
- Q99638
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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