Aurora Kinase B Antikörper (C-Term)
Kurzübersicht für Aurora Kinase B Antikörper (C-Term) (ABIN7448917)
Target
Alle Aurora Kinase B (AURKB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-Aurora B IHC Antibody, Affinity Purified
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Homologie
- Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 300 and C-term
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Isotyp
- IgG
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Applikationshinweise
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ICC-IF: 1:100 - 1:500
IHC: 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 100 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Aurora Kinase B (AURKB)
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Andere Bezeichnung
- Aurora B
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Hintergrund
- Background: Aurora B is the central enzymatic unit of the chromosomal passenger complex (CPC). In the CPC, Aurora B is associated with the passenger proteins inner centromeric protein (INCENP), survivin, and borealin. Aurora B is a serine-threonine protein kinase essential for chromosome segregation and cytokinesis. Specific roles for Aurora B have been demonstrated in cohesin dissociation from centromeres as well as condensin I binding to chromatin.F112. Substrates of Aurora B kinase activity include desmin, septin 1, INCENP, RAC GTPase activating protein 1, and centromeric protein A.
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Gen-ID
- 9212
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NCBI Accession
- NP_004208
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UniProt
- Q96GD4
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Pathways
- T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
Target
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