RAPGEF2 Antikörper (AA 975-1025)
Kurzübersicht für RAPGEF2 Antikörper (AA 975-1025) (ABIN7448889)
Target
Alle RAPGEF2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 975-1025
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Verwendungszweck
- Rabbit anti-PDZ-GEF1 IHC Antibody, Affinity Purified
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Homologie
- Mouse,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,African elephant,Chinese hamster,Thirteen-lined ground squirrel,Northern white-cheeked gibbon
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 975 and 1025
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Isotyp
- IgG
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Applikationshinweise
- 1:100 to 1:500. Epitope retrieval with citrate Buffer pH 6.0 is recommended for FFPE tissue sections.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
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Andere Bezeichnung
- PDZ-GEF1
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Hintergrund
- Background: PDZ-GEF1 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity.
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Gen-ID
- 9693
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NCBI Accession
- NP_055062
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UniProt
- Q9Y4G8
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Pathways
- Neurotrophin Signalübertragung
Target
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