RPA1 Antikörper (AA 350-400)
Kurzübersicht für RPA1 Antikörper (AA 350-400) (ABIN7448781)
Target
Alle RPA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 350-400
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Verwendungszweck
- Rabbit anti-RPA70 IHC Antibody, Affinity Purified
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Homologie
- Rabbit,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Northern white-cheeked gibbon,Tasmanian devil,Gray short-tailed opossum
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 350 and 400
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Isotyp
- IgG
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anti-Replication Protein A1, 70kDa (RPA1) antibody
RPA1 Reaktivität: Human, Affe WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 4C4 unconjugated
anti-Replication Protein A1, 70kDa (RPA1) (C-Term) antibodyRPA1 Reaktivität: Human WB, IP, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Replication Protein A1, 70kDa (RPA1) antibodyRPA1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Maus Monoclonal 4C4 unconjugated
anti-Replication Protein A1, 70kDa (RPA1) antibodyRPA1 Reaktivität: Human, Affe WB, ELISA, IHC, FACS, IF/ICC Wirt: Maus Monoclonal unconjugated
anti-Replication Protein A1, 70kDa (RPA1) (AA 1-616) antibodyRPA1 Reaktivität: Human WB, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Replication Protein A1, 70kDa (RPA1) antibodyRPA1 Reaktivität: Human, Affe WB, IF, FACS, IHC (p), EIA Wirt: Maus Monoclonal 4C4 unconjugated
anti-Replication Protein A1, 70kDa (RPA1) (Internal Region) antibodyRPA1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Replication Protein A1, 70kDa (RPA1) antibodyRPA1 Reaktivität: Human, Maus WB, IP, ICC Wirt: Maus Monoclonal unconjugated
anti-Replication Protein A1, 70kDa (RPA1) (AA 1-240) antibodyRPA1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Replication Protein A1, 70kDa (RPA1) (AA 367-616) antibodyRPA1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RPA1 (Replication Protein A1, 70kDa (RPA1))
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Andere Bezeichnung
- RPA70
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Hintergrund
- Background: Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32 kDa (RPA2), and 14 kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.
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Gen-ID
- 6117
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NCBI Accession
- NP_002936
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UniProt
- P27694
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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