Prohibitin Antikörper (AA 222-272)
Kurzübersicht für Prohibitin Antikörper (AA 222-272) (ABIN7448745)
Target
Alle Prohibitin (PHB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 222-272
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Verwendungszweck
- Rabbit anti-Prohibitin IHC Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Bovine,Dog,Rabbit,Guinea pig_10141,Pig,Panda,Cat,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Naked mole rat,Gray short-tailed opossum,Little brown bat,Chinese hamster,Northern white-cheeked gibbon,Crab-eating macaque,Tasmanian devil,Thirteen-lined ground squirrel,Small-eared galago
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 222 and 272
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Prohibitin (PHB)
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Andere Bezeichnung
- Prohibitin
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Hintergrund
- Background: Prohibitin (PHB) has been identified as a tumor suppressor protein that can repress E2F-mediated transcription and arrest cell cycle progression. It has recently been shown to associate with members of the minichromosome maintenance complex such as MCM2, MCM5, and MCM7 and therefore is thought to impart its growth inhibitory effects via association with the replication machinery. Prohibitin is also implicated in regulating mitochondrial respiration and playing a role in aging.
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Gen-ID
- 5245
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NCBI Accession
- NP_002625
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UniProt
- P35232
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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