General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) Antikörper

Produktnummer ABIN7448586

Der Kaninchen Polyklonal anti-General Transcription Factor 3C Polypeptide 3 Antikörper (ABIN7448586) detektiert spezifisch General Transcription Factor 3C Polypeptide 3 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) Antikörper (ABIN7448586)

Target: General Transcription Factor 3C Polypeptide 3 (GTF3C3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 475-525

Verwendungszweck: Rabbit anti-GTF3C3/TFIII1C102 IHC Antibody, affinity purified

Homologie: Mouse,Rat,X. tropicalis,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Crab-eating macaque,African elephant,Ferret,Little brown bat,Zebra finch,Naked mole rat,Green anole,Northern white-cheeked gibbon,Tasmanian devil,White-tufted-ear marmoset,Gray short-tailed opossum,Small-eared galago

Aufreinigung: Affinity Purified

Immunogen: Between AA 475 and 525

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Antigendetails

Target: General Transcription Factor 3C Polypeptide 3 (GTF3C3)

Andere Bezeichnung: GTF3C3/TFIIIC102

Hintergrund: Background: General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.

Gen-ID: 9330

NCBI Accession: NP_036218

UniProt: Q9Y5Q9